Bone is the material with which the orthopaedic surgeon deals. In the longitudinal direction, significant differences were observed only between young age groups and the other two age groups middle aged and elderly, whereas no significant difference was found between the middle aged and elderly groups. Methods femoral heads were obtained after surgical removal from age and sex matched groups of patients with either osteoporosis op, after a fractured neck of femur, or osteoarthritis oa and compared with a normal group. Many authors have examined the mechanical properties of bone cement and the various factors that affect its mechanical behavior. The flexibility properties of the bone are provided by the collagen material of the bone. Bmd, mechanical properties, testing, strength evaluation. Bone loss is greatest in the first 12 months of corticosteroid therapy, continues at a lower rate thereafter, and predominantly affects trabecular bone.
Anisotropy in the compressive mechanical properties of bovine cortical bone and the mineral and protein constituents ekaterina novitskayaa. Compared with the bone of adults, that of children had a lower modulus of elasticity, a lower. Every technique of assessing bone architecture or the properties of a given. Mechanical loading and bone frontiers research topic. The mechanical properties of bones are governed by the same principles as those of manmade loadbearing structures. As for teeth, they also are replaced by artificial materials which are called upon to perform the mechanical functions of the original tooth. The mechanical properties ofnormal bone have been studied extensively reilly andburstein 1974 but relatively little work hasbeen published describing how disease modifies these properties. Bone structure has a decisive influence on its mechanical properties, and three types of cells that build it can be distinguished. Mechanical properties and performance of materials samples of engineering materials are subjected to a wide variety of mechanical tests to measure their strength, elastic constants, and other material properties as well as their performance under a variety of actual use conditions and environments. The bone tissue is a viscouselastic material whose mechanical properties are affected by its deformation grade. The mechanical properties of these scaffolds are within the lower range of human cancellous bone, which has wide range of compressive strength 112 mpa and youngs modulus 1005000 mpa. Bone is a composite of mainly collagen and minerals hydroxyapatite, or calcium collagen has a low e, high tensile strength, low compressive strength hydroxyapatite is stiff, brittle, high compressive strength anisotropic material that can resist different types of. Generally, there are two possibilities for the determination of the mechanical strength of bone cements. For cortical bone, important changes of the elastic properties values have been clearly shown in ageing but not.
The determination of the mechanical properties of bone is a study that has attracted the interest of perhaps as diverse a group of researchers as any biomaterials topic. Strength of bones is dependent upon the material, the microscopic structure and the shape of the whole bone. To further examine structuremechanical function relationships, local deformation behavior along the tendontobone attachment was determined using local image. While most of the studies have concentrated more on elastic properties of bone 7, 45, 30, 86, yield properties have also been extracted from microindentation data based on inverse methods 111, 70. Cash fraction d, where ash fraction is the weight of the bone after ashing divided by the dry weight. The material behavior of cortical bone is anisotropic. Introduction 1 the femur, or thigh bone, is the most proximal. The percent bone volume is the proportion of the volume of interest voi occupied by bone where bone is defined as any nonporous region within the voi. The mechanical properties of machined cortical bone specimens from human femora and tibiae were determined in tension, torsion, and compression for a population ranging in age from twentyone to eightysix years. Correlations between structural and mechanical properties of human trabecular femur bone 39 therefore, the main purpose of the studies conducted is to determine the structural and mechanical properties of bone tissue, to search for correlations between them, and to attempt to describe such correlations by means of mathematical relationships. This research topic is focused on recent advances in our understanding of effects of mechanical loading on the skeleton, encompassing the full spectrum of laboratory and clinical research. However, it has lower youngs modulus and fracture toughness with brittle nature. Evans and king documented the mechanical properties oftrabecular bone from multiple locations in the proximal human femur.
Osteons should affect the mechanical properties of the cortex in several ways. Salt lake city, utah 84109 national institute of aging, gerontology research center, baltimore, md 21224 introduction. Neutrophils are continuously released from the bone marrow bm, and this release is accelerated during inflammation. Mechanical properties of cranial bone 497 attempt to correlate the mechanical properties with position fig. Effect of grounded bone powder addition on the mechanical. Mechanical testing of bone and the bone implant interface helps you assess these properties by explaining how to do mechanical testing of bone and the bone implant interface for bone related research. In addition to microct imaging, the mechanical properties of rat cortical bone as a function of age were assessed with threepoint bending testing. We first consider the mechanical properties of single osteons, and then consider cortical bone. Among them hydroxyapatite is most widely studied bioactive and biocompatible material. Mechanical properties of bone cements springerlink. Gaynor evans department of anatomy, the university of michigan medical school, aim arbor, michigan 481 04 abstract tensile breaking load, strength. Relations among mechanical properties, collagen fibers, and calcification in adult human cortical bone. Osteons and the cosserat micro elasticity of compact bone.
Mechanical properties of cortical bone and their relationships with age, gender, composition and microindentation properties in the elderly author links open overlay panel mohammad j. The variability in elastic properties for trabecular and cortical bone is demonstrated nicely by tabulated data in currey 45 and rice 202, which have been presented in modi. Mechanical properties of various mammalian tendons m. Despite important applications for finite element modeling of loose implants, the.
N2 the mechanical properties of bone include all of the properties measured and all of the mathematical complexities developed by engineers to understand and use solid materials to build houses, cars and electronics. The evaluation was based on the assessment of mechanical properties compressive strength and indirect tensile strength measured at 7, 28, 90, 180 and 270 days. Mechanical properties and histology cortical bone from. These onaxis yield strains were compared to those measured previously for highdensity 0. Variables that influence the mechanical properties, such as handling characteristics, strain rate, loading modes, additives, porosity, blood inclusion, in vivo environment, temperature, etc. Only a few authors have described electrical properties of the human bone tissue saha and williams 1989, skinner et al 2001. The purpose of this study was to correlate changes in cortical and cancellous bone mass, structure, and dynamics with mechanical properties during and after the first reproductive cycle in rats.
Human trabecular bone, femoral head, bone mineral density, mechanical properties. The aim of the research described in this paper is to specify the mechanical properties of the skull relevant to the biomechanics of head injury. Articles explore the basic mechanical principles of bone related study and how to conduct mechanical testing of bone specimens. Mechanical properties of bone are also of interest in trauma biomechanics and in efforts to prevent injury to the body. It is necessary to reduce the dispersion of test results to allow for quantitative evaluation of the mechanical properties of trabecular bone and is. There is an extensive literature on age changes in the anatomy, physiology, bio chemistry, mineralization, and pathology of human bone, considerably less on age. Hence, it is required to produce a biomaterial with good mechanical properties. This article presents a comprehensive survey on the reported mechanical properties of bone cement. Differences in the tensile properties of bone from younger and older men can be explained by histological differences in the bone. The importance of specifying these variables in reporting test results on the mechanical properties of bone cement is pointed out. The mechanical properties of bone seen in the force displacement examples are expressions of the mechanical properties of the hard tissue. The biomechanics laboratory, case western reserve university, 10900 euclid avenue, cleveland, ohio 44106. The different mechanical properties give the strength of bone.
However, the ability of vertebrates to adapt their bone structure to the imposed loading, in terms of both the evolution of a genetic plan for the skeleton and the ability to acutely modify this plan by cellular activity, results in a structure that is highly complex and, when. These variables mean that there is a range of measured properties for bone, and so values given in tables will always be an average, with quite a considerable spread possible in the data. This paper reports a characterization of stressstrain response of the humerus, clavicle and scapula through impact studies followed by property estimation. However, in human primary osteoporosis, whether cartilage lesions would also affect properties beneath trabecular bone remains unknown. This paper presents an experimental investigation on the effect of using bone powder bp, as a cement addition, on the mechanical properties of cement mortar. No significant differences were found between the mechanical properties of male and female specimens. Micromechanical investigation revealed a decrease in strength in entheses with mineral defects. This is a repository copy of mechanical properties of nacre and highly mineralized bone. Electromechanical properties of bones abstract bones are an integral part of the human body that exhibit piezoelectric properties, meaning that when stress is applied to the bone, the bone produces a current within itself. A bimodal characterization, apr 2012, nantes, france.
Variables that influence the mechanical properties, such as handling characteristics, strain rate, loading modes, additives, porosity, blood inclusion, in vivo environment. Alexander department of pure and applied zoology, university of leeds, leeds ls2 9jt accepted i october 1985 with 3 figures in the text dynamic tensile tests have been performed, using physiologically relevant frequencies and stress. The main cause of failure in total hip replacement is aseptic loosening which is associated with the formation of a periprosthetic fibrous interface tissue. Pdf the mechanical properties of bone in osteoporosis. Bone is a natural composite material made up of a cellular component, and. Mechanical properties of cattle bone tissue and natural. Hydrogels are not generally considered as the material of choice for large bone defects, due to their weak mechanical properties. Specimens of femoral cortical bone from eighteen subjects between two and fortyeight years old were loaded in bending. The mechanical properties of bone tissue in children.
The effectiveness of surgical bone cement must be viewed in the light of its mechanical properties. Ability of the muscle to transmit an impulse ap from one part of the fibre to another part. Pdf mechanical properties and the hierarchical structure. Abstract specimens of femoral cortical bone from eighteen subjects between two and fortyeight years old were loaded in bending. Stott, journalthe journal of bone and joint surgery. The interaction of stress and strain provides insight into the mechanical behaviour of material properties in bone when deforming under load36. The tarsal bones are essentially shells of compact bones filled with spongy bone, fat, marrow substance, blood, etc. Scale is of importance in discussing bone architecture as the structure is hierarchical and complex. Mechanical properties of some biomaterials and bone are summarized in table 1. On some properties of bone functional adaptation phenomenon useful in mechanical design 51. Bovine trabecular bone is known to be denser and less porous than the human trabecular bone jiang et al 1998, keaveny et al 2001, t. Compared with the bone of adults, that of children had a lower modulus of. Evaluation on mechanical properties of a single trabecular in.
Comparison of microstructural and mechanical properties of. On a macro scale, bone is an organ that performs well defined functions in the body, as well as a tissue composed of bone lamella forming a compact and cancellous bone. Number of cycles to failure, nf maximum cyclic stress. This paper presents the basic fundamentals of the mechanical properties of bones and the biomechanics of bone fracture. Mechanical testing of bone and the bone implant interface helps you assess these properties by explaining how to do mechanical testing of bone and the bone implant interface for bone related. Trabecular bone teeth material properties of hard tissues structural properties of hard tissues mechanical properties of trabecular tissue contribution of components to whole bone strength viscoelastic properties of bone viscoelastic model of bone properties bone as a composite. Bone mechanical properties in healthy and diseased states ncbi. Mechanical properties of nacre and highly mineralized bone. Doitpoms tlp library structure of bone and implant.
It has been shown that the mechanical properties of bone vary at different structural levels. Additionally, a novel microindentation technique, termed reference point indentation rpi,that is capable of in vivo testing was used to assess the mechanical properties of rat bone. In this study, we explored the differences in local trabecular properties between osteoporosis patients with and without. Observations of osteon stiffness and understanding of its role in the generalized continuum representation of bone are important in that they bear upon the question of the toughness of bone. However, literature evaluating the mechanical properties of a single trabecular yields a wide dispersion of the results. However, in recent years it has been con firmed that bone strength does not solely depend on its mass, but also on its geometric, structural and material properties. This study compared the mechanical properties of mature neutrophils within the bm and the circulating blood, as well as the role of microtubule rearrangement in the release of neutrophils from the bm in rats. Influence of the mechanical environment upon the healing of.
Furthermore, material, structural and mechanical testing will be performed to determine how important early callus formation and size are to the physical properties of the healed bone. Bone introduction information on the following lesions is available in this section. Anisotropy in the compressive mechanical properties of bovine. An experimental comparison of living and dead bone in rats. The mechanical properties of bone are affected by crosslinking of the organic matrix 35. A bigger study with 10 animals per group is underway to confirm the results from this pilot study. Perhapsthemostnatural test of amaterials mechanical properties is the tensiontest,in which astriporcylinderofthematerial,havinglengthlandcrosssectionalareaa,isanchoredatone end and subjected to an axial load p a load acting along the specimens long axis at the other. Mechanical properties and histology of cortical bone from younger and older men f. Keaveny university of california, san francisco, california and university of california, berkeley, california elise f. In particular, the potential of the bone to resist fracture is affected by these physiologic and mechanical sources. The nonliving intercellular material of bone consists of an organic component called collagen a fibrous protein arranged in long strands or. The effect of ageing and osteoarthritis on the mechanical. Bingharn engineering building, case western reserve university, 10900.
Youngs modulus for trabecular bone varies from approximately 0. On some properties of bone functional adaptation phenomenon. The mechanical properties of bone are as variable as its structure. Consequently, some knowledge of its mechanical properties is of importance for an understanding of the mechanism and management of fractures, as well as the design of prosthetic or orthotic appliances and protective gear, e. Mechanical properties of bone strength and stiffness that depend upon form size, shape can be altered in response to load increased bone mineral content osteoblast activity osteoclast activity degree of increase in bone density directly proportional to the. Mechanical testing of bone and the boneimplant interface. The weighted sum of the stressstrain curves of the treated bones was far lower than that of the untreated bone, indicating a strong molecular andor mechanical. Mechanical properties of rat bone marrow and circulating. In addition, the anisotropic structure of bone means that its mechanical properties must be considered in two orthogonal directions. Cancellous and cortical bone mechanical properties and. Bone structure composition is cortical, cancellous mineral.
Mechanical properties of trabecular bone by a nondestructive compression testing approach frank linde, charlotte buch goosthgen, ivan hvid, buntoeng pongsoipetch, and soosren bentzen engineering in medicine 2016 17. This article contains a survey of known properties of bone and teeth, with an. Characterization of bone material properties and microstructure in. Correlations between structural and mechanical properties.
Ultrastructure and microstructure and effects on mechanical properties. Micromechanical properties of the tendontobone attachment. The mechanical properties can be achieved from the different tests i. The condution velocity of an impulse in skeletal muscle fiber is slow. Osteoporosis is a disease involving a marked decrease in bone mass, and it is most often found in postmenopausal women. Mar 31, 2015 degeneration of cartilage will change load distribution, affecting bone remodeling progress and trabecular structure and strength. Cbmt is a noninvasive, dynamic 3point bending test that makes direct, functional measurements of the mechanical properties of cortical bone in ulnas of living people. Relationship between mechanical properties and bone mineral. Objective to determine the material properties of the subchondral bone plate in patients with osteoarthritis or osteoporosis. Bone bone chemical composition and physical properties. Bone can be regarded as a dynamic tissue in vivo and as a relatively stable structural material when observed in vitro.
The collagen content gives the bone the ability to support tense loads. Prediction of mechanical properties of human trabecular bone. Anisotropy in the compressive mechanical properties of. Gaynor francis gaynor, 1907 mechanical properties of bone. Material that are piezoelectric can similarly exhibit the. Two types or forms of bones are found in the footirregularly shaped bones the tarsals and miniature long bones the metatarsals and the phalanges. However osteons within whole bone are also under some axial restraint from the adjacent osteons and therefore would experience a similar stiffening. Mechanical testing, mechanical properties and anisotropic characteristics of bone slideshare uses cookies to improve functionality and performance, and to provide you with relevant advertising. The effect of ageing and osteoarthritis on the mechanical properties of cartilage and bone in the human knee joint. Elastic modulus, flexural yield strength, ultimate strength, and crackgrowth toughness. The characteristics of mechanical properties such as youngs modulus initial modulus of elasticity, ultimate tensile stress, ultimate tensile strain, ultimate. The mechanical properties of whole bones, bone tissue, and the bone implant interfaces are as important as their morphological and structural aspects.
Mechanical properties and the hierarchical structure of bone. Jakob schwiedrzik a b 1 suwanwadee thaiwichai a james p. Get a printable copy pdf file of the complete article 140k, or click on a page image below to browse page by page. Factors affecting the mechanical properties of bone. Bone biomechanicsoverview primary mechanical functions. Mechanical properties of cancellous bone is said to be depended on quantities and orientation of trabecular bone. As noted earlier in the chapter, the mechanical properties of normal cortical bone are related to the mineral content of the tissue as. Though it is well established that mechanical loading provides an essential stimulus for skeletal growth and maintenance, there have been major advances recently in terms of our understanding of the. If you continue browsing the site, you agree to the use of cookies on this website.
1240 202 478 476 1115 904 859 1206 891 1040 1447 1390 1264 153 123 344 65 1159 1280 1517 1184 1326 112 409 872 245 35 85 764